Biotin and derivatives
Medchemexpress LLC Biotin-PEG3-acid 100mg | 252881-76-8 | 100 MG
Biotin-PEG3-acid is a biotin-labeled polyethylene glycol (PEG3) linker containing a terminal carboxylic acid. It is supplied as a purified research-grade small molecule for use in PROTAC synthesis and biotinylation applications.
- Biotin-labeled PEG3 linker with terminal carboxylic acid.
- Designed for PROTAC synthesis and biotinylation workflows.
- High purity, 98.0%.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed at 4°C; in solution store at -80°C for long-term stability.
- Available in 100 MG and larger pack sizes for research use.
![Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203007.png-250.jpg)
Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG
Bis-PEG2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker bearing N-hydroxysuccinimide (NHS) ester reactive groups at both ends, designed for antibody-agent conjugation via amine-coupling chemistry for research use.
- Noncleavable two-unit PEG linker for antibody-agent conjugation.
- N-hydroxysuccinimide (NHS) ester reactive groups for amine coupling.
- High purity, 99.2%.
- Molecular weight 400.34 g/mol.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation may be required.
- Storage: powder at -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
- Available in multiple pack sizes, including 250 MG.
Medchemexpress LLC Biotin-PEG3-iodoacetamide | 2306161-26-0 | 97.0% | 10 MG
Biotin-PEG3-iodoacetamide is a PEG-based linker combining a biotin tag, a three-unit PEG spacer, and an iodoacetamide reactive group. It selectively alkylates cysteine residues under mild conditions to introduce a biotin handle for affinity capture, detection, and enrichment workflows.
- Selective cysteine labeling via iodoacetamide chemistry.
- Biotin tag enables high-affinity streptavidin capture.
- PEG3 spacer improves solubility and reduces steric hindrance.
- Suitable for protein labeling, pull-downs, and detection assays.
- Provided as a small-molecule reagent for research use.
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | MFCD22683276 | 98.0% | 476.48 g/mol | C19H32N4O10 | 25 MG
Azido-PEG6-NHS ester is a bifunctional PEG-based reagent containing an azide group for bioorthogonal click chemistry and an N-hydroxysuccinimide (NHS) ester for coupling to primary amines. It is commonly used as a linker in antibody-drug conjugate and PROTAC synthesis, and for general bioconjugation applications.
- Bifunctional: azide for CuAAC/SPAAC and NHS ester for amine coupling.
- PEG6 spacer improves solubility and reduces steric hindrance.
- High purity for reliable conjugation reactions.
- Suitable for ADC and PROTAC linker installation and bioconjugation workflows.
- Available in small-scale packaging compatible with research applications.
Medchemexpress LLC Azido-PEG3-SS-NHS | 95.0% | 436.50 | C15H24N4O7S2 | 5 MG
Azido-PEG3-SS-NHS is a cleavable three-unit polyethylene glycol (PEG) linker intended for bioconjugation and antibody-drug conjugate synthesis. It contains an azide for click chemistry, a disulfide bond for reductive cleavage, and an N-hydroxysuccinimide (NHS) ester for amine coupling.
- Contains azide for copper-catalyzed and strain-promoted click reactions.
- Contains NHS ester for efficient conjugation to primary amines.
- Includes a cleavable disulfide spacer for intracellular release.
- Suitable for linker design in ADC, PROTAC, and other bioconjugation workflows.
- Supplied as a liquid, colorless to light yellow, with reported purity of 95.0%.
Medchemexpress LLC Azido-PEG16-NHS ester | 00-00-0 | 99.9% | C39H72N4O20 | 10MG
Azido-PEG16-NHS ester is a PEG-based bifunctional linker featuring an azide moiety and an N-hydroxysuccinimide (NHS) ester. It enables conjugation to primary amines via the NHS ester and subsequent click chemistry using the azide, making it suitable for bioconjugation, labeling, and PROTAC synthesis. The reagent is provided at high purity and is soluble in DMSO for convenient formulation.
![eMolecules Medchem Express / N-piperidine Ibrutinib (hydrochloride) / 5mg / 600899891 / HY-130983 / / 2231747-18-3 / [null] / 422.920 / C22H23ClN6O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465889.JPG-250.jpg)
eMolecules Medchem Express / N-piperidine Ibrutinib (hydrochloride) / 5mg / 600899891 / HY-130983 / / 2231747-18-3 / [null] / 422.920 / C22H23ClN6O
Medchem Express / N-piperidine Ibrutinib (hydrochloride) / 5mg / 600899891 / HY-130983 / / 2231747-18-3 / [null] / 422.920 / C22H23ClN6O
Medchemexpress LLC Bis-PEG25-NHS ester | 2221948-96-3 | 99.8% | 1413.55 g/mol | C62H112N2O33 | 250 MG
Bis-PEG25-NHS ester is a homobifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester groups, used for amine-directed bioconjugation in PROTAC and ADC synthesis. It provides a hydrophilic spacer to improve solubility and facilitates cleavable linker chemistry.
- High purity (99.8%).
- Homobifunctional PEG linker with two NHS ester groups.
- Molecular weight 1413.55 g/mol and formula C62H112N2O33.
- Suitable for PROTAC and ADC linker chemistry and general amine-directed conjugation.
- Available in multiple pack sizes including 25 mg, 50 mg, 100 mg, 250 mg, 500 mg, and 1 g.
- Store sealed, away from moisture at -20°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 5X1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Medchemexpress LLC NHS-SS-biotin | 122266-55-1 | MFCD28505564 | 98.0% | 504.64 g/mol | C19H28N4O6S3 | 100 MG
NHS-SS-biotin is a cleavable disulfide-containing biotin linker with an N-hydroxysuccinimide (NHS) ester reactive group. It is used to introduce a biotin tag onto primary amines and as a reducible linker in antibody-drug conjugate synthesis and other bioconjugation workflows.
- Cleavable disulfide linker for reductive release.
- NHS ester reactive toward primary amines.
- Useful for protein and peptide biotinylation and affinity capture.
- Available in small-scale quantities suitable for research applications.
- Purity typically 98.0% as provided in supplier documentation.
Medchemexpress LLC IL-13 Human Biotin 20ug
IL-13 protein is a cytokine involved in allergic inflammation immune response to parasites and B cell proliferation IL-13 Protein Human (Biotinylated HEK293 Avi-His) is the recombinant human-derived IL-13 protein expressed by HEK293 with C-Avi C-6 His labeled tag
Medchemexpress LLC (S,E)-TCO-NHS ester | 1610931-22-0 | MFCD24386372 | ≥98.0% | 267.28 g/mol | C13H17NO5 | 10 MG
TCO-NHS ester (axial) is a trans-cyclooctene N-hydroxysuccinimide ester used as an amine-reactive building block for bioorthogonal conjugation. It enables rapid inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine partners and is suitable for labeling or modifying amine-containing small molecules and biomolecules in organic media. The reagent is supplied as a purified solid with supporting analytical documentation for research use.
- Amine-reactive NHS ester for efficient conjugation.
- Fast bioorthogonal iEDDA reactivity with tetrazines.
- Suitable for labeling and bioconjugation of biomolecules.
- High purity for reproducible experimental results.
- Analytical documentation available (SDS, COA, H-NMR).
Medchemexpress LLC Biotin methyl ester 250mg
Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research